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J Clin Pathol. 1980 Nov;33(11):1106-9. doi: 10.1136/jcp.33.11.1106.
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Prevalence of hepatitis B e antigen and its antibody as detected by radioimmunoassays.采用放射免疫分析法检测乙肝e抗原及其抗体的流行情况。
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Serum HBsAg, HBeAg, anti-HBe, and hepatitis B viral DNA in asymptomatic carriers in Taiwan.台湾无症状携带者的血清乙肝表面抗原、乙肝e抗原、乙肝e抗体及乙肝病毒DNA
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2
Hepatitis B virus DNA and e antigen in serum from blood donors in the United Kingdom positive for hepatitis B surface antigen.英国乙型肝炎表面抗原呈阳性的献血者血清中的乙型肝炎病毒DNA和e抗原。
Br Med J (Clin Res Ed). 1985 Mar 2;290(6469):663-4. doi: 10.1136/bmj.290.6469.663.

本文引用的文献

1
New specificities in Australia antigen positive sera distinct from the Le Bouvier determinants.澳大利亚抗原阳性血清中与勒布维耶决定簇不同的新特异性。
J Immunol. 1972 Nov;109(5):1017-21.
2
e antigen and anti-e in the serum of asymptomatic carrier mothers as indicators of positive and negative transmission of hepatitis B virus to their infants.无症状携带母亲血清中的e抗原和抗-e作为乙肝病毒母婴传播阳性和阴性的指标。
N Engl J Med. 1976 Apr 1;294(14):746-9. doi: 10.1056/NEJM197604012941402.
3
High prevalence of e antigen among healthy blood donors carrying hepatitis B surface antigen in Japan.日本乙肝表面抗原携带者中健康献血者的e抗原高流行率。
Vox Sang. 1977;32(5):296-9. doi: 10.1111/j.1423-0410.1977.tb00649.x.
4
e-Antigen and anti-e in two categories of chronic carriers of hepatitis B surface antigen.乙型肝炎表面抗原两类慢性携带者中的e抗原和抗e抗体
Vox Sang. 1978;34(4):231-8. doi: 10.1111/j.1423-0410.1978.tb02473.x.
5
Anti-HBe and subtypes of HBsAg among asymptomatic HBsAg carriers.无症状HBsAg携带者中的抗-HBe及HBsAg亚型
Vox Sang. 1979;36(2):109-14. doi: 10.1111/j.1423-0410.1979.tb04409.x.
6
Hepatitis Be antigen and antibody in hepatitis B surface antigen positive blood donors.乙肝表面抗原阳性献血者中的乙肝e抗原和抗体
J Clin Pathol. 1979 Feb;32(2):132-5. doi: 10.1136/jcp.32.2.132.
7
Letter: Decreasing frequency of e antigen with age in serum of symptom-free carriers of hepatitis B antigen.信函:乙肝抗原无症状携带者血清中e抗原随年龄增长频率降低。
Lancet. 1976 Sep 11;2(7985):577-8. doi: 10.1016/s0140-6736(76)91829-8.
8
A new antigen-antibody system. Clinical significance in long-term carriers of hepatitis B surface antigen.一种新的抗原-抗体系统。对乙肝表面抗原长期携带者的临床意义。
JAMA. 1975 Jan 27;231(4):356-9. doi: 10.1001/jama.231.4.356.

乙肝表面抗原阳性献血者中HBeAg和抗-HBe检测的意义

Significance of tests for HBeAg and anti-HBe in HBsAg positive blood donors.

作者信息

Dow B C, Macvarish I, Barr A, Crawford R J, Mitchell R

出版信息

J Clin Pathol. 1980 Nov;33(11):1106-9. doi: 10.1136/jcp.33.11.1106.

DOI:10.1136/jcp.33.11.1106
PMID:7440758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1146346/
Abstract

A sensitive radioimmunoassay method for HBeAg and anti-HBe allowed 98.4% of HBsAg positive blood donors to be classified. HBeAg was more prevalent in blood donors under 30 years of age and anti-HBe was more prevalent in those over 30 years. The mean HBsAg concentration was four times greater in donors with HBeAg than in those with anti-HBe. No significant associations were found with sex, blood groups, or HBsAg subtypes. It is likely that this test system will be extremely useful to blood transfusion centres and hepatitis reference laboratories in the future.

摘要

一种用于检测HBeAg和抗-HBe的灵敏放射免疫分析方法,可对98.4%的HBsAg阳性献血者进行分类。HBeAg在30岁以下的献血者中更为普遍,而抗-HBe在30岁以上的献血者中更为普遍。HBeAg阳性献血者的平均HBsAg浓度是抗-HBe阳性献血者的四倍。未发现与性别、血型或HBsAg亚型有显著关联。该检测系统未来可能对输血中心和肝炎参考实验室极为有用。