乙肝表面抗原阳性献血者中HBeAg和抗-HBe检测的意义
Significance of tests for HBeAg and anti-HBe in HBsAg positive blood donors.
作者信息
Dow B C, Macvarish I, Barr A, Crawford R J, Mitchell R
出版信息
J Clin Pathol. 1980 Nov;33(11):1106-9. doi: 10.1136/jcp.33.11.1106.
Abstract
A sensitive radioimmunoassay method for HBeAg and anti-HBe allowed 98.4% of HBsAg positive blood donors to be classified. HBeAg was more prevalent in blood donors under 30 years of age and anti-HBe was more prevalent in those over 30 years. The mean HBsAg concentration was four times greater in donors with HBeAg than in those with anti-HBe. No significant associations were found with sex, blood groups, or HBsAg subtypes. It is likely that this test system will be extremely useful to blood transfusion centres and hepatitis reference laboratories in the future.
摘要
一种用于检测HBeAg和抗-HBe的灵敏放射免疫分析方法，可对98.4%的HBsAg阳性献血者进行分类。HBeAg在30岁以下的献血者中更为普遍，而抗-HBe在30岁以上的献血者中更为普遍。HBeAg阳性献血者的平均HBsAg浓度是抗-HBe阳性献血者的四倍。未发现与性别、血型或HBsAg亚型有显著关联。该检测系统未来可能对输血中心和肝炎参考实验室极为有用。
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