Malatová Z, Pomfy M, Marsala J
Act Nerv Super (Praha). 1983 Mar;25(1):43-8.
Activity of cholinacetyltransferase (ChAT. EC 2.3.1.6) and acetylcholinesterase (AChE, EC 3.1.1.7) was monitored during occlusion of arteria cerebri media dx. (MCA) in five areas of the brain cortex, in nucleus caudatus and in the thalamus of the ipsilateral and contralateral hemisphere. After 1 hour of MCA occlusion ChAT and AChE activity was reduced in the ischemised region of the hemisphere, i. e. in gyrus ectosylvius anterior and gyrus sylvius anterior, whereas after 4 hours of occlusion the differences were not significant. In nc. caudatus and thalamus the activity of enzymes during ischemia did not change much.
在大脑中动脉右支(MCA)闭塞期间,监测了大脑皮质五个区域、尾状核以及同侧和对侧半球丘脑的胆碱乙酰转移酶(ChAT,EC 2.3.1.6)和乙酰胆碱酯酶(AChE,EC 3.1.1.7)的活性。大脑中动脉闭塞1小时后,半球缺血区域(即颞上回前部和颞下回前部)的ChAT和AChE活性降低,而闭塞4小时后,差异不显著。在尾状核和丘脑中,缺血期间酶的活性变化不大。