• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

犬局部脑缺血期间胆碱能酶活性

Cholinergic enzyme activity during partial brain ischemia in the dog.

作者信息

Malatová Z, Pomfy M, Marsala J

出版信息

Act Nerv Super (Praha). 1983 Mar;25(1):43-8.

PMID:6858592
Abstract

Activity of cholinacetyltransferase (ChAT. EC 2.3.1.6) and acetylcholinesterase (AChE, EC 3.1.1.7) was monitored during occlusion of arteria cerebri media dx. (MCA) in five areas of the brain cortex, in nucleus caudatus and in the thalamus of the ipsilateral and contralateral hemisphere. After 1 hour of MCA occlusion ChAT and AChE activity was reduced in the ischemised region of the hemisphere, i. e. in gyrus ectosylvius anterior and gyrus sylvius anterior, whereas after 4 hours of occlusion the differences were not significant. In nc. caudatus and thalamus the activity of enzymes during ischemia did not change much.

摘要

在大脑中动脉右支(MCA)闭塞期间,监测了大脑皮质五个区域、尾状核以及同侧和对侧半球丘脑的胆碱乙酰转移酶(ChAT,EC 2.3.1.6)和乙酰胆碱酯酶(AChE,EC 3.1.1.7)的活性。大脑中动脉闭塞1小时后,半球缺血区域(即颞上回前部和颞下回前部)的ChAT和AChE活性降低,而闭塞4小时后,差异不显著。在尾状核和丘脑中,缺血期间酶的活性变化不大。

相似文献

1
Cholinergic enzyme activity during partial brain ischemia in the dog.犬局部脑缺血期间胆碱能酶活性
Act Nerv Super (Praha). 1983 Mar;25(1):43-8.
2
[The effects of ischemia and postischemic reperfusion on the brain cholinergic system of the rat].[缺血及缺血后再灌注对大鼠脑胆碱能系统的影响]
Masui. 1989 Mar;38(3):350-6.
3
Effect of partial ischemia and axotomy on activities of cholinergic enzymes in lower motor neurons of the dog.局部缺血和轴突切断对犬下运动神经元胆碱能酶活性的影响。
Act Nerv Super (Praha). 1986 Jun;28(2):87-95.
4
Distribution of choline acetyltransferase and acetylcholinesterase in the nervous system of the dog.
Physiol Bohemoslov. 1983;32(2):129-34.
5
Effect of axotomy on cholinergic enzyme activities in the spinal cord and sciatic nerve of the dog.轴突切断术对犬脊髓和坐骨神经中胆碱能酶活性的影响。
Physiol Bohemoslov. 1987;36(2):153-60.
6
[Changes in acetylcholine level and its related enzyme activities in rat brain following focal ischemia].
No To Shinkei. 1998 Jan;50(1):39-44.
7
Neurochemical and histochemical studies of the effect of a lesion of the nucleus cuneiformis on the cholinergic innervation of discrete areas of the rat brain.楔状核损伤对大鼠脑离散区域胆碱能神经支配影响的神经化学和组织化学研究。
Brain Res. 1979 Jul 6;170(1):113-22. doi: 10.1016/0006-8993(79)90944-2.
8
Depression of acetylcholinesterase synthesis following transient cerebral ischemia in rat: pharmacohistochemical and biochemical investigation.大鼠短暂性脑缺血后乙酰胆碱酯酶合成的抑制:药物组织化学与生物化学研究
Gen Physiol Biophys. 1999 Mar;18(1):57-71.
9
Histochemical and biochemical study on the acetylcholinesterase and choline acetyltransferase in the brain and spinal cord of frog, Rana esculenta.食用蛙脑和脊髓中乙酰胆碱酯酶及胆碱乙酰转移酶的组织化学与生物化学研究
J Hirnforsch. 1988;29(2):157-63.
10
Effect of D-Ala2-met-enkephalinamide and morphine on the activity of choline acetyltransferase and acetylcholinesterase in rat brain.D-丙氨酸2-甲硫氨酸脑啡肽酰胺和吗啡对大鼠脑内胆碱乙酰转移酶及乙酰胆碱酯酶活性的影响。
Acta Physiol Pol. 1981 May-Jun;32(3):233-7.