Norn M
Acta Ophthalmol (Copenh). 1983 Feb;61(1):141-9. doi: 10.1111/j.1755-3768.1983.tb01404.x.
Examination of 1029 subjects disclosed 30-60 micron-sized frog's egg-like lipid deposits subconjunctivally and episclerally in 34%. The prevalence was found to rise steadily with increasing age to a maximum between 70 and 80 (52%). The prevalence declined after the age of 80. Both sexes were equally represented, except in the age groups over 70, where females predominated. In 48% lipid deposits were presented in both eyes, located nasally, temporally, inferiorly, and superiorly in decreasing order of frequency. Vertical location alone was found in 13%. The number of lipid globules was the greatest horizontally (median value nasally 20, temporally 30) and the smallest vertically (median value inferiorly 8, superiorly 15). The lipid deposits were generally found in relation to anterior ciliary arteries, most frequently off the upper corner of the horizontal muscles. In no more than 13% were such deposits seen as pads bearing no relation to vessels, and in 1% between tendon fibres, likewise non-related to vessels. No relation was noticed to presence of pinguecula, pterygium, and scleral plaques, nor to blood pressure or particularly thick conjunctiva. Lipid deposits were rarer in cases with an extraordinarily thin conjunctiva. Presence of lipid deposits may possible be accountable for by injuries of the arterial wall due to eye muscle movements with subsequent exudation of lipids into the surrounding episcleral connective tissue.
对1029名受试者进行检查后发现，34%的人在结膜下和巩膜上有30 - 60微米大小的蛙卵样脂质沉积。研究发现，患病率随年龄增长稳步上升，在70至80岁之间达到最高（52%）。80岁以后患病率下降。除70岁以上年龄组女性占主导外，男女比例相当。48%的患者双眼均有脂质沉积，按频率递减顺序分布于鼻侧、颞侧、下方和上方。仅垂直分布的占13%。脂质球数量水平方向最多（鼻侧中位数为20，颞侧为30），垂直方向最少（下方中位数为8，上方为15）。脂质沉积通常与睫状前动脉有关，最常见于水平肌上角外侧。不超过13%的脂质沉积表现为与血管无关的斑块，1%位于肌腱纤维之间，同样与血管无关。未发现与睑裂斑、翼状胬肉和巩膜斑块的存在有关，也与血压或结膜特别增厚无关。结膜异常薄的病例中脂质沉积较少见。脂质沉积的出现可能是由于眼球运动导致动脉壁损伤，随后脂质渗出到周围的巩膜结缔组织中。
