Koering M J
Am J Anat. 1983 Apr;166(4):429-43. doi: 10.1002/aja.1001660405.
Ovaries obtained from 18 adult, regularly cycling rhesus monkeys were evaluated to determine the status of preantral follicle development at various stages throughout the menstrual cycle. The ovaries were serially sectioned, and all preantral follicles on every 20th section were classified as developing or atretic, counted and/or measured, and grouped according to size. Results from this study revealed (1) that a significant increase (P less than 0.05) occurred in the mean percentage of developing preantral follicles greater than 100 microns in diameter during the periovulatory period, suggesting that follicles in this size range had developed a sensitivity to the unique hormonal milieu present during that stage of the cycle; (2) that similar numbers of primordial and developing preantral follicles were present in the right and left ovaries of a pair, showing that neither ovary had a predominance over the other; (3) that the mean number of developing preantral follicles varied directly with the size of the primordial follicle pool; (4) that atresia was minimal with no significant differences between the various stages of the cycle in any size group; and (5) that polyovular follicles were abundant in certain pairs of ovaries, but could not be related to age or stage of cycle.
对18只成年、月经周期正常的恒河猴的卵巢进行评估，以确定整个月经周期不同阶段窦前卵泡的发育状况。将卵巢连续切片，每20张切片上的所有窦前卵泡被分类为发育中或闭锁型，进行计数和/或测量，并按大小分组。本研究结果显示：（1）在排卵期，直径大于100微米的发育中窦前卵泡的平均百分比显著增加（P<0.05），这表明该大小范围内的卵泡对周期该阶段存在的独特激素环境产生了敏感性；（2）一对卵巢的左右卵巢中存在数量相似的原始卵泡和发育中窦前卵泡，表明两侧卵巢无优势之分；（3）发育中窦前卵泡的平均数量与原始卵泡池的大小直接相关；（4）闭锁情况极少，任何大小组在周期的不同阶段之间均无显著差异；（5）某些卵巢对中多卵卵泡丰富，但与年龄或周期阶段无关。
