Musto B, Greco R, Calabrò R, Marsico F
G Ital Cardiol. 1979;9(4):368-73.
43 patients, 3 days to 12 years old, presented 68 paroxysms of supraventricular tachycardia and 2 crises of atrial flutter. 6 patients had a WPW syndrome and only 7 had an associated cardiac disease; the remaining had no other complaint but the arrhythmia. Verapamil, administered in the dose of 0.125-0.25 mg/Kg intravenously, interrupted critically the tachycardia in virtually all cases. The flutter was converted to atrial fibrillation with a slower ventricular rate. No adverse effects were observed but in two cases: one had a cardiac arrest promptly relieved and another a ventricular bradycardia corrected by atropine. Both cases had received an overdose of the drugs.
43例年龄在3天至12岁的患者，出现68次阵发性室上性心动过速发作和2次心房扑动发作。6例患者患有预激综合征，只有7例伴有心脏病；其余患者除心律失常外无其他不适。静脉注射维拉帕米，剂量为0.125 - 0.25mg/kg，几乎在所有病例中都能迅速终止心动过速。心房扑动转变为心室率较慢的心房颤动。未观察到不良反应，但有两例除外：一例心脏骤停经及时抢救缓解，另一例心室心动过缓经阿托品纠正。这两例均用药过量。
