Williams P L, Corbett M
Ann Rheum Dis. 1983 Jun;42(3):276-9. doi: 10.1136/ard.42.3.276.
Two patients who developed widespread severe avascular necrosis of bone while on steroid replacement therapy are described. One, a diabetic, underwent yttrium-90 pituitary ablation for retinopathy and developed avascular necrosis within 18 months of starting prednisolone. The other, who had Addison's disease, developed avascular necrosis within 14 months of starting cortisol replacement therapy. Both cases came to bilateral total hip replacement.
本文描述了两名在接受类固醇替代治疗期间发生广泛严重骨缺血性坏死的患者。其中一名糖尿病患者因视网膜病变接受了钇-90垂体消融术，并在开始使用泼尼松龙后的18个月内发生了骨缺血性坏死。另一名患有艾迪生病的患者在开始皮质醇替代治疗后的14个月内发生了骨缺血性坏死。两例均接受了双侧全髋关节置换术。
