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库欣病伴双侧股骨头缺血性坏死并垂体卒中

Cushing's disease presenting with avascular necrosis of the femoral heads and complicated by pituitary apoplexy.

作者信息

Wicks I P, Calligeros D, Kidson W, Bertouch J V

机构信息

Department of Rheumatology, Prince Henry Hospital, Sydney, Australia.

出版信息

Ann Rheum Dis. 1987 Oct;46(10):783-6. doi: 10.1136/ard.46.10.783.

DOI:10.1136/ard.46.10.783
PMID:3689004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1003389/
Abstract

A case of Cushing's disease presenting with avascular necrosis of the femoral heads is described. Eighteen months after the onset of hip symptoms the patient developed pituitary apoplexy and presented to hospital as a medical emergency. Endogenous hypercortisolism is a rare and important cause of avascular necrosis of bone.

摘要

本文描述了一例库欣病伴双侧股骨头缺血性坏死的病例。髋部症状出现18个月后，患者发生垂体卒中，并作为内科急症入院。内源性皮质醇增多症是一种罕见但重要的骨缺血性坏死病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/98e713133884/annrheumd00408-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/07815e2127e4/annrheumd00408-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/ba672b1c20c9/annrheumd00408-0064-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/98e713133884/annrheumd00408-0065-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/07815e2127e4/annrheumd00408-0064-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/ba672b1c20c9/annrheumd00408-0064-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e0a/1003389/98e713133884/annrheumd00408-0065-a.jpg

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1
Cushing's disease presenting with avascular necrosis of the femoral heads and complicated by pituitary apoplexy.库欣病伴双侧股骨头缺血性坏死并垂体卒中
Ann Rheum Dis. 1987 Oct;46(10):783-6. doi: 10.1136/ard.46.10.783.
2
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引用本文的文献

1
Avascular Necrosis in Patients With Cushing Syndrome.库欣综合征患者的缺血性坏死
JCEM Case Rep. 2025 Feb 5;3(2):luaf001. doi: 10.1210/jcemcr/luaf001. eCollection 2025 Feb.
2
Pituitary apoplexy in cushing's disease: a single center study and systematic literature review.库欣病垂体卒中：单中心研究和系统文献回顾。
Pituitary. 2024 Aug;27(4):335-344. doi: 10.1007/s11102-024-01411-1. Epub 2024 Jun 8.
3
Spontaneous bone infarction of the distal femur in a patient with Cushing's disease: a case report.库欣病患者股骨远端自发性骨梗死：一例报告

本文引用的文献

1
AVASCULAR NECROSIS OF BONE IN CUSHING'S SYNDROME.
Radiology. 1964 Dec;83:1068-70. doi: 10.1148/83.6.1068.
2
IDIOPATHIC AVASCULAR NECROSIS OF THE HEAD OF THE FEMUR. A STUDY OF FIFTY-TWO CASES.特发性股骨头缺血性坏死。52例病例研究。
J Bone Joint Surg Am. 1964 Mar;46:267-82.
3
Human osteoblastic activity. III. The effect of cortisone on lamellar osteoblastic activity.人类成骨细胞活性。III. 可的松对板层状成骨细胞活性的影响。
Henry Ford Hosp Med Bull. 1961 Mar;9:97-9.
Bone Rep. 2021 Feb 18;14:100756. doi: 10.1016/j.bonr.2021.100756. eCollection 2021 Jun.
4
Avascular necrosis of bone complicating corticosteroid replacement therapy.皮质类固醇替代治疗并发的骨缺血性坏死。
Ann Rheum Dis. 1983 Jun;42(3):276-9. doi: 10.1136/ard.42.3.276.
5
Physiopathology of Cushing's disease.库欣病的病理生理学
Endocr Rev. 1983 Winter;4(1):22-43. doi: 10.1210/edrv-4-1-22.
6
Cushing's syndrome--killing disease: discriminatory value of signs and symptoms aiding early diagnosis.库欣综合征——致命疾病：有助于早期诊断的体征和症状的鉴别价值
Lancet. 1982 Sep 18;2(8299):646-9. doi: 10.1016/s0140-6736(82)92749-0.
7
Avascular necrosis of the femoral head as the presenting manifestation of Cushing's disease.
Clin Orthop Relat Res. 1973 Nov-Dec(97):69-73. doi: 10.1097/00003086-197311000-00011.
8
Corticosteroid-induced avascular necrosis. A clinical study of seventy-seven patients.
J Bone Joint Surg Am. 1971 Jul;53(5):859-73.
9
The role of fat embolism in the etiology of corticosteroid-induced avascular necrosis: clinical and experimental results.
Clin Orthop Relat Res. 1978 Jan-Feb(130):68-80.