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去甲肾上腺素在人胎盘、脐带和胎膜中的代谢失活。

Metabolic inactivation of noradrenaline in human placenta, umbilical cord and fetal membranes.

作者信息

Saarikoski S

出版信息

Br J Obstet Gynaecol. 1983 Jun;90(6):525-7. doi: 10.1111/j.1471-0528.1983.tb08960.x.

DOI:10.1111/j.1471-0528.1983.tb08960.x
PMID:6860599
Abstract

Metabolic inactivation of noradrenaline (NA) was studied in human placenta, umbilical vessels, Wharton's jelly and fetal membranes. Highest degradation capacity was observed in the placenta and fetal membranes, where the NA was inactivated by both monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT). No MAO and COMT activity was found in the cord jelly and the activities in umbilical vessels were very low.

摘要

在人胎盘、脐血管、华通胶和胎膜中研究了去甲肾上腺素(NA)的代谢失活。在胎盘和胎膜中观察到最高的降解能力,其中NA可被单胺氧化酶(MAO)和儿茶酚-O-甲基转移酶(COMT)灭活。在脐带胶质中未发现MAO和COMT活性,脐血管中的活性非常低。

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