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一种双动刺激电极及其在碰撞试验行为版本中的应用。

A dual moveable stimulating electrode and its application to the behavioral version of the collision test.

作者信息

Miliaressis E, Philippe L

出版信息

Brain Res Bull. 1983 Apr;10(4):573-7. doi: 10.1016/0361-9230(83)90157-0.

DOI:10.1016/0361-9230(83)90157-0
PMID:6860983
Abstract

The construction and testing of a dual moveable electrode for chronic stimulation in small mammals are described. The assembly is lightweight (0.9 g), its components are completely re-usable, and the two electrodes may be independently advanced in steps as small as 80 microns over a maximum vertical excursion of 6 mm. The unit performed as well as fixed electrodes do in daily behavioral tests conducted over a 3 month period. Ipsiversive rotation was elicited by stimulation of 15 pontine-mesencephalic sites in a single rat. Behavioral evidence for the collision of heterodromic action potentials in circling-relevant fibers was obtained in 4 position sets.

摘要

本文描述了一种用于小型哺乳动物慢性刺激的双可移动电极的构建与测试。该组件重量轻(0.9克),其组件可完全重复使用,并且两个电极可在最大垂直行程6毫米内以小至80微米的步长独立推进。在为期3个月的日常行为测试中,该装置的表现与固定电极相同。在一只大鼠中,通过刺激15个脑桥 - 中脑位点诱发了同侧旋转。在4个位置组中获得了与转圈相关纤维中异向动作电位碰撞的行为证据。

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A dual moveable stimulating electrode and its application to the behavioral version of the collision test.一种双动刺激电极及其在碰撞试验行为版本中的应用。
Brain Res Bull. 1983 Apr;10(4):573-7. doi: 10.1016/0361-9230(83)90157-0.
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Psychophysical method for mapping behavioral substrates using a moveable electrode.使用可移动电极绘制行为基质的心理物理学方法。
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Robust, highly customizable, and economical multi-channel electrode for chronic multi-unit recording in behaving animals.坚固、高度可定制且经济的多通道电极,用于行为动物的慢性多单元记录。
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Localization of reward-relevant neurons in the pontine tegmentum: a moveable electrode mapping study.脑桥被盖中与奖赏相关神经元的定位:一项可移动电极图谱研究。
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引用本文的文献

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Medial forebrain bundle lesions fail to structurally and functionally disconnect the ventral tegmental area from many ipsilateral forebrain nuclei: implications for the neural substrate of brain stimulation reward.内侧前脑束损伤未能在结构和功能上使腹侧被盖区与许多同侧前脑核断开连接:对脑刺激奖赏神经基质的影响。
J Neurosci. 1998 Oct 15;18(20):8515-33. doi: 10.1523/JNEUROSCI.18-20-08515.1998.
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Mesencephalic substrate of reward: axonal connections.奖赏的中脑基质:轴突连接
J Neurosci. 1996 May 15;16(10):3511-20. doi: 10.1523/JNEUROSCI.16-10-03511.1996.