Robertson E G, Holsinger K K, Neer K J, Garcia S J
Am J Obstet Gynecol. 1978 Sep 15;132(2):192-7. doi: 10.1016/0002-9378(78)90923-7.
Maturity studies are reported on 204 women with high-risk pregnancies. Estimates of fetal maturity were made prenatally by the use of ultrasonic measurements, the lecithin/sphingomyelin (L/S) ratio, and a gestational index based on amniotic fluid creatinine, urea nitrogen, and cytology. These estimates were compared with the neonatal pediatric estimate of maturity. The gestational score agreed with pediatric maturity to within 14 days in 95 per cent of the cases. Estimates of L/S ratio distinguished between mature and immature infants in 86 per cent of the cases. Ultrasound could estimate gestational age only to within 14 days in 75 per cent of the cases, and the disagreements were greatest where either growth retardation or macrosomia was present. However, ultrasound is more useful in estimating fetal size and abnormalities of growth pattern. An estimate of gestational age by gestational score aids management, particularly where growth retardation is present, enabling a decision about delivery to be made even though the infant is very small and has an immature L/S ratio.
对204例高危妊娠女性进行了成熟度研究。产前通过超声测量、卵磷脂/鞘磷脂（L/S）比值以及基于羊水肌酐、尿素氮和细胞学的妊娠指数来估计胎儿成熟度。将这些估计值与新生儿儿科成熟度估计值进行比较。妊娠评分在95%的病例中与儿科成熟度的误差在14天以内。L/S比值估计在86%的病例中能够区分成熟和未成熟婴儿。超声在75%的病例中只能将胎龄估计在14天以内，并且在存在生长迟缓或巨大儿的情况下，差异最大。然而，超声在估计胎儿大小和生长模式异常方面更有用。通过妊娠评分估计胎龄有助于管理，特别是在存在生长迟缓的情况下，即使婴儿非常小且L/S比值不成熟，也能做出关于分娩的决定。
