Rey F, Felber J P
Clin Biochem. 1983 Feb;16(1):23-5. doi: 10.1016/s0009-9120(83)94296-0.
Radioimmunoassays for plasma pancreatic enzymes, especially cationic trypsin, are good tools to diagnose pancreatic pathology. The trypsin assay is very sensitive. Its detection limit is 300 pg/ml. The plasma level of this enzyme appears to be representative of pancreatic function. This assay was shown to be valuable in the diagnosis of acute pancreatitis, and to follow the course of the disease. In chronic pancreatitis, it enables assessment of residual function of the organ. In the terminal stage of this disease, very low values were found. Used as a screening test, the assay allowed early detection of cystic fibrosis.
用于检测血浆中胰腺酶，尤其是阳离子胰蛋白酶的放射免疫测定法，是诊断胰腺疾病的良好工具。胰蛋白酶测定非常灵敏。其检测限为300皮克/毫升。这种酶的血浆水平似乎代表胰腺功能。该测定法在急性胰腺炎的诊断及疾病病程监测中显示出价值。在慢性胰腺炎中，它能够评估胰腺器官的残余功能。在该疾病的终末期，会发现胰蛋白酶值极低。作为一种筛查测试，该测定法可实现对囊性纤维化的早期检测。
