Stagg B H, Wood T P
Ann Clin Biochem. 1979 May;16(3):147-51. doi: 10.1177/000456327901600131.
This review describes the development and application of a novel test to determine levels of human immunoreactive trypsin, an enzyme produced solely by the pancreas, in biological fluids. Being organ-specific, the assay of immunoreactive trypsin should be an ideal marker of pancreatic function, and this is supported by the results of a number of clinical and research investigations. Use of this assay in studies of chronic pancreatitis, juvenile-onset diabetes, and cystic fibrosis has yielded much valuable data, and it is expected that further research will lead to an improved understanding of these and other conditions associated with the pancreas in health and disease.
本综述描述了一种新型检测方法的开发与应用，该方法用于测定生物体液中人类免疫反应性胰蛋白酶的水平，胰蛋白酶是一种仅由胰腺产生的酶。由于具有器官特异性，免疫反应性胰蛋白酶的检测应该是胰腺功能的理想标志物，许多临床和研究调查结果都支持这一点。在慢性胰腺炎、青少年发病型糖尿病和囊性纤维化研究中使用该检测方法已经产生了许多有价值的数据，预计进一步的研究将有助于更好地理解这些与胰腺相关的健康和疾病状况以及其他状况。
