Campbell W L
Dis Colon Rectum. 1983 Jul;26(7):445-8. doi: 10.1007/BF02556523.
Cathartic colon is an infrequent and severe manifestation of chronic irritant laxative abuse. Little is known of its natural history after cathartics are stopped. Previous reported cases have shown residual roentgen abnormalities on follow-up examinations. A case is presented of cathartic colon caused by more than 70 years of laxative abuse that demonstrated complete reversal of the roentgen changes four months after stopping the medication. Some pathophysiologic correlates of this dramatic reversibility are discussed.
泻剂性结肠是慢性滥用刺激性泻药的一种罕见且严重的表现。对于停用泻药后其自然病程了解甚少。既往报道的病例在随访检查中显示有残留的X线异常。本文报告一例因70多年滥用泻药导致的泻剂性结肠病例,该病例在停药四个月后X线改变完全逆转。文中讨论了这种显著可逆性的一些病理生理相关因素。