Haanaes O C, Bergmann A
Eur J Respir Dis. 1983 May;64(4):294-7.
Corticosteroid therapy is held to facilitate activity of tuberculous disease. This retrospective study is an analysis of 1355 patients suffering from tuberculosis who had been discharged from a chest hospital during a 9-year period starting in 1971. Those on corticosteroid therapy for the last 6 months prior to diagnosis, were included. There were no new cases of tuberculosis among these, but 40 patients or 3 per cent had reactivation of former disease. The findings should be representative of the national prevalence. Despite increasing use of corticosteroids, there is no indication that the number of reactivated cases associated with such treatment has increased during the years. A majority of our patients were suffering from serious corticosteroid-demanding diseases which might in themselves be as causative as the drug therapy in activating the tuberculosis.
皮质类固醇疗法被认为会促使结核病活动。这项回顾性研究分析了1971年起的9年期间从一家胸科医院出院的1355例结核病患者。纳入了在诊断前最后6个月接受皮质类固醇治疗的患者。这些患者中没有新的结核病病例，但有40例患者（3%）既往疾病复发。这些发现应能代表全国患病率。尽管皮质类固醇的使用越来越多，但没有迹象表明与这种治疗相关的复发病例数在这些年里有所增加。我们的大多数患者患有严重的需要使用皮质类固醇的疾病，这些疾病本身在激活结核病方面可能与药物治疗一样具有病因性。
