Burnelli S, Guarnieri A, Varoli L, Cesaroni M R, Scapini G
Farmaco Sci. 1983 May;38(5):340-51.
The synthesis of some homologues of 2-(4-biphenylyl)-3-hydroxypropionic acid, the separation of related diastereoisomers, their attribution to erythro and threo series, and resolution of the optical antipodes are described. The antiinflammatory activity--initially tested by carrageenin assay--proves generally influenced by steric configuration and is interesting for the isohexanoic derivative.