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子宫切除术可促进大鼠的接受性行为。

Hysterectomy facilitates proceptive behavior in rats.

作者信息

Ahdieh H B, Wade G N

出版信息

Horm Behav. 1983 Mar;17(1):134-7. doi: 10.1016/0018-506x(83)90022-3.

DOI:10.1016/0018-506x(83)90022-3
PMID:6862389
Abstract

The effects of hysterectomy on proceptive behavior were investigated using several doses of estradiol benzoate (EB) and progesterone (P) in female rats. One week after surgery, ovariectomized (OV) and ovariectomized-hysterectomized (OH) rats were given three daily injections of 1.0 or 2.0 micrograms EB followed by 0.5 mg P or oil on the fourth day and were tested for solicitation 4 hr later. The same animals received 1.0 or 2.0 micrograms EB plus 0.1 mg P, or 4.0 micrograms EB plus oil on the same schedule a week following the first test and were tested again. Ovariectomized-hysterectomized animals receiving 0.5 mg P, regardless of the EB dose, showed significantly higher solicitation scores than OV animals, but the scores of the EB-primed OV and OH rats receiving 0.1 mg P or oil vehicle did not differ.

摘要

利用几种剂量的苯甲酸雌二醇(EB)和孕酮(P),研究了子宫切除术对雌性大鼠接受性行为的影响。手术后一周,对卵巢切除(OV)和卵巢切除-子宫切除(OH)的大鼠每天注射三次1.0或2.0微克EB,在第四天注射0.5毫克P或油,4小时后测试其求偶行为。在第一次测试一周后,相同的动物按照相同的时间表接受1.0或2.0微克EB加0.1毫克P,或4.0微克EB加油,并再次进行测试。无论EB剂量如何,接受0.5毫克P的卵巢切除-子宫切除动物的求偶得分显著高于OV动物,但接受0.1毫克P或油性载体的EB预处理的OV和OH大鼠的得分没有差异。

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