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[人体离体肝脏灌注期间及之后血浆氨基酸的变化。简要临床报告]

[Changes in plasma amino acids during and following isolated liver perfusion in the human. Brief clinical report].

作者信息

Weidler B, von Bormann B, Biscoping J, Aigner K, Tonn J, Krahl M, Hempelmann G

出版信息

Infusionsther Klin Ernahr. 1983 Apr;10(2):58-61.

PMID:6862620
Abstract

Plasma amino acids have been analysed during isolated perfusion of the liver in dogs. Aromatic amino acids increased, also the branched chain amino acids showed a small rise. Thus no signs of hepatic failure could be detected. To evaluate early signs of hepatic failure in 2 patients scheduled for isolated liver perfusion, the plasma amino acids where analysed. Corresponding to the results obtained in animals, aromatic acids increased, whereas branched chain amino acids remained constant or rose. Even in the postoperative course no signs of deterioration of plasma amino acids could be detected.

摘要

在犬肝脏离体灌注期间对血浆氨基酸进行了分析。芳香族氨基酸增加,支链氨基酸也有小幅上升。因此未检测到肝衰竭迹象。为评估2例计划进行肝脏离体灌注患者的肝衰竭早期迹象,对其血浆氨基酸进行了分析。与在动物身上获得的结果一致,芳香族氨基酸增加,而支链氨基酸保持不变或上升。即使在术后过程中,也未检测到血浆氨基酸恶化的迹象。

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