Sharpe W D
Health Phys. 1983;44 Suppl 1:149-54. doi: 10.1097/00004032-198306001-00012.
Histologic examination of 35 femora from 25 New Jersey radium workers with measured preterminal 226Ra burdens between background levels (less than or equal to 0.0042) and 1.78 muCi demonstrated that 10 of the 11 whose burdens exceeded background had radium osteonecrosis, including 6 of 7 whose burdens were above background levels but below 0.1 muCi. Ten of 16 cases with radium osteonecrosis had cancer as did 5 of 9 who did not have radium osteonecrosis. The number of cases is too small to be confident of any association between bone necrosis and cancer, but the presence of changes consistent with radium osteonecrosis in 6 of 14 radium workers whose 226Ra burdens could not be measured above background levels is disturbing.
对25名新泽西镭作业工人的35根股骨进行组织学检查，这些工人的终末前226镭负荷量经测量在本底水平（小于或等于0.0042）至1.78微居里之间。结果显示，11名负荷量超过本底的工人中有10人患有镭骨坏死，其中7名负荷量高于本底水平但低于0.1微居里的工人中有6人患病。16例镭骨坏死病例中有10例患癌症，9例未患镭骨坏死的工人中有5例患癌症。病例数量过少，无法确定骨坏死与癌症之间是否存在任何关联，但在14名226镭负荷量无法测量出高于本底水平的镭作业工人中，有6人出现了与镭骨坏死相符的变化，这令人不安。
