Ginzberg R D, Morest D K
Hear Res. 1983 May;10(2):227-46. doi: 10.1016/0378-5955(83)90056-4.
Individual afferent and efferent nerve fibers were identified and traced in Golgi-impregnated cochleas of cats from newborn to one month old. Afferent radial fibers project radially without varicosities to terminate at the base of one or two inner hair cells. Outer spiral fibers have both radial and spiral orientations within the organ of Corti, do not form varicosities while crossing the base of the tunnel, and spiral for long distances in the outer spiral bundles. They contact many outer hair cells of more than one row both en passant and by small terminal branchlets. Two separate groups of efferent fibers are identifiable. Thin efferent fibers with many large varicosities spiral for long distances in the inner and tunnel spiral bundles; varicosities in the inner spiral bundle may contact radial afferent fibers or hair cells, depending on age. Thick radial efferent fibers course radially through the tunnel spiral bundle and across the upper part of the tunnel, often in fascicles. They contact a few outer hair cell bases by large terminals. The spiral expanse of the terminals is limited. These fibers are most common in the more basal turns of the organ. The present results confirm the anatomical separation of radial and spiral afferent fiber systems and identify two separate efferent populations beyond the neonatal period in the cat. The major features of afferent innervation discernible in Golgi-impregnated cochleas are present at birth, although some simplification of afferent fibers probably occurs during the first postnatal week. In contrast, the efferent fiber pattern undergoes important changes during the first few weeks after birth. In mature animals, the fine spiral efferents probably contact only afferent fibers, whereas the thick radial efferents may contact both outer hair cells and spiral afferent fibers. The possibility that some individual efferents branch to both inner and outer hair cell regions in the older cats cannot be ruled out.
在新生至1月龄猫的高尔基染色耳蜗中，对单个传入和传出神经纤维进行了识别和追踪。传入的放射状纤维呈放射状投射，无曲张，终止于一两个内毛细胞的基部。外螺旋纤维在柯蒂氏器内既有放射状又有螺旋状取向，在穿过隧道基部时不形成曲张，并在外螺旋束中螺旋延伸很长距离。它们通过沿途和小的终末分支与不止一排的许多外毛细胞接触。可识别出两组不同的传出纤维。有许多大曲张的细传出纤维在内螺旋束和隧道螺旋束中螺旋延伸很长距离；内螺旋束中的曲张可能根据年龄接触放射状传入纤维或毛细胞。粗的放射状传出纤维呈放射状穿过隧道螺旋束并越过隧道上部，通常成束状。它们通过大的终末与少数外毛细胞基部接触。终末的螺旋范围有限。这些纤维在该器官的更基部的螺旋中最为常见。目前的结果证实了放射状和螺旋状传入纤维系统在解剖学上的分离，并确定了猫在新生儿期之后存在两个不同的传出群体。在高尔基染色的耳蜗中可辨别的传入神经支配的主要特征在出生时就已存在，尽管在出生后的第一周可能会发生一些传入纤维的简化。相比之下，传出纤维模式在出生后的头几周会发生重要变化。在成熟动物中，细的螺旋传出纤维可能仅接触传入纤维，而粗的放射状传出纤维可能接触外毛细胞和螺旋状传入纤维。不能排除在老年猫中一些单个传出纤维分支到内毛细胞和外毛细胞区域的可能性。
