Carlson H E, Wasser H L, Levin S R, Wilkins J N
J Clin Endocrinol Metab. 1983 Aug;57(2):334-8. doi: 10.1210/jcem-57-2-334.
To study the effect of meals on PRL secretion, serum PRL was measured after the ingestion of mixed meals and specific single macronutrients by normal men and women. In men, only protein feeding significantly stimulated PRL secretion. In women, protein meals as well as a standard mixed meal and a liquid mixed meal resulted in PRL release. Fat, glucose, and a nonnutrient meal had no consistent effect on serum PRL. Serum TSH was not altered by any of the meals, and serum GH and cortisol showed few changes. We conclude that PRL stimulation by meals may be of occasional clinical significance, principally in confusing the diagnosis of hyperprolactinemic states, especially in women. Dietary protein is probably the agent responsible for PRL secretion induced by meals.
为研究进餐对催乳素（PRL）分泌的影响，对正常男性和女性摄入混合餐及特定单一宏量营养素后测定血清PRL。在男性中，仅摄入蛋白质显著刺激PRL分泌。在女性中，蛋白质餐以及标准混合餐和流质混合餐均导致PRL释放。脂肪、葡萄糖和无营养餐对血清PRL无一致影响。任何餐食均未改变血清促甲状腺激素（TSH），血清生长激素（GH）和皮质醇变化甚微。我们得出结论，进餐对PRL的刺激可能偶尔具有临床意义，主要在于混淆高催乳素血症状态的诊断，尤其是在女性中。膳食蛋白质可能是进餐诱导PRL分泌的介质。
