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抗原诱导的支气管痉挛中血清补体和嗜酸性粒细胞计数的变化

Changes of serum complement and eosinophil count in antigen induced bronchospasm.

作者信息

Hsieh K H

出版信息

Ann Allergy. 1978 Sep;41(3):182-5.

PMID:686513
Abstract

By using house dust antigens, in addition to the relation between specific IgE antibody, precipitin antibody and bronchial provocation test (BPT), the changes of serum complement activities and eosinophil counts after BPT were studied. Decreased serum concentrations of C4 and Factor B were found in three of 15 skin-test positive asthmatic children, thus confirming the involvement of complement in the pathogenesis of immediate type BPT reaction. Eosinophil counts tended to increase after BPT but the increase did not correlate with the occurence of the immediate type BPT reaction.

摘要

通过使用屋尘抗原,除了研究特异性IgE抗体、沉淀素抗体与支气管激发试验(BPT)之间的关系外,还研究了BPT后血清补体活性和嗜酸性粒细胞计数的变化。在15名皮肤试验阳性的哮喘儿童中,有3名儿童的血清C4和B因子浓度降低,从而证实补体参与了速发型BPT反应的发病机制。BPT后嗜酸性粒细胞计数有增加的趋势,但这种增加与速发型BPT反应的发生无关。

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Changes of serum complement and eosinophil count in antigen induced bronchospasm.抗原诱导的支气管痉挛中血清补体和嗜酸性粒细胞计数的变化
Ann Allergy. 1978 Sep;41(3):182-5.
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引用本文的文献

1
Decreased production of interleukin-2 receptors after immunotherapy to house dust.
J Clin Immunol. 1988 May;8(3):171-7. doi: 10.1007/BF00917563.
2
Decreased production of CD8 (T8) antigen after immunotherapy.免疫治疗后CD8(T8)抗原产生减少。
J Clin Immunol. 1989 Mar;9(2):111-8. doi: 10.1007/BF00916938.