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[非霍奇金淋巴瘤——临床诊断与治疗的当前进展]

[Non-Hodgkins's lymphomas - current aspects of clinical diagnosis and therapy].

作者信息

Huhn D

出版信息

Klin Wochenschr. 1983 May 2;61(9):435-43. doi: 10.1007/BF02664330.

DOI:10.1007/BF02664330
PMID:6865273
Abstract

Non-Hodgkin-Lymphomas (NHL), classified according to "Kiel" or Rappaport", may be subdivided into those with low or with high malignancy. Corresponding to clinical stage and to histological subtype, therapeutic recommendations are discussed. 1. Limited stage: An irradiation with curative intention seems possible. In cases with unfavourable histology relapses are frequent, and an additional or exclusive therapy with cytostatics appears to be of increasing importance. 2. Advanced stages and favourable histology: The value of an early and intensive use of cytostatics is questioned. 3. Advanced stages and unfavourable histology: Cure of the lymphoma seems feasible when intensive cytostatic regimes are applied.

摘要

非霍奇金淋巴瘤(NHL),根据“基尔”或“拉帕波特”分类,可细分为低度恶性或高度恶性。根据临床分期和组织学亚型,讨论了治疗建议。1. 局限性期:进行根治性放疗似乎可行。组织学不良的病例复发频繁,因此使用细胞抑制剂进行辅助或单独治疗显得越来越重要。2. 晚期且组织学良好:早期和强化使用细胞抑制剂的价值受到质疑。3. 晚期且组织学不良:应用强化细胞抑制方案时,淋巴瘤的治愈似乎可行。

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本文引用的文献

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Germinal center cell lymphomas: prognostic significance of their histopathological differentiation.生发中心细胞淋巴瘤:其组织病理学分化的预后意义
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Assessment of bone marrow histology in the malignant lymphomas (non-Hodgkin's): correlation with clinical factors for diagnosis, prognosis, classification and staging.
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