Gattiker H H, Wiltshaw E, Galton D A
Cancer. 1980 May 15;45(10):2627-32. doi: 10.1002/1097-0142(19800515)45:10<2627::aid-cncr2820451023>3.0.co;2-0.
Two hundred and nine cases of non-Hodgkin's lymphoma have been analyzed retrospectively for the occurrence of spontaneous regression (SR). Complete, partial or minor SR was found in 18 out of 140 cases with nodular lymphoma and in 2 out of 69 cases with diffuse lymphoma. Thus, SR occurs far more frequently in nodular lymphoma than in the diffuse type. Within the nodular lymphoma group, SR is associated with long survival. It occurred in previously treated and untreated patients and in nodal and extranodal disease; the duration varied from a few weeks to many years but lasted one year or more in 7 cases with complete or partial SR.
对209例非霍奇金淋巴瘤病例进行了回顾性分析,以研究自发缓解(SR)的发生情况。在140例结节性淋巴瘤病例中,有18例出现完全、部分或轻度SR;在69例弥漫性淋巴瘤病例中,有2例出现SR。因此,SR在结节性淋巴瘤中的发生频率远高于弥漫性淋巴瘤。在结节性淋巴瘤组中,SR与长期生存相关。它发生在既往接受过治疗和未接受过治疗的患者中,以及淋巴结和结外病变中;持续时间从几周至多年不等,但在7例完全或部分SR的病例中持续了一年或更长时间。