3β-羟基-13α-氨基-13,17-开环-5α-雄甾烷-17-酸-13,17-内酰胺对-双（2-氯乙基）氨基苯氧基乙酸酯（NSC 294859）对实验动物肿瘤和白血病系统的活性。
Activity of 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam-p-bis(2-chloroethyl)aminophenoxyacetate (NSC 294859) on experimental animal tumor and leukemia systems.
作者信息
Catsoulacos P
出版信息
Oncology. 1983;40(4):290-2. doi: 10.1159/000225746.
PMID:6866424
Abstract
3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam-p-bis(2-chloroethyl)amino-phenoxyacetate, a modified steroidal alkylating agent, is active in the treatment of colon 26 tumor, B16 melanoma and P388 leukemia.
摘要
3β-羟基-13α-氨基-13,17-开环-5α-雄甾烷-17-酸-13,17-内酰胺-对-双（2-氯乙基）氨基苯氧乙酸酯，一种经过修饰的甾体烷基化剂，在治疗结肠26肿瘤、B16黑色素瘤和P388白血病方面具有活性。
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