Ferriman D, Purdie A W
Postgrad Med J. 1983 Jan;59(687):17-20. doi: 10.1136/pgmj.59.687.17.
An analysis of 467 patients with oligomenorrhoea and/or hirsuties in respect to duration of the menstrual cycle, body hair growth, ovarian size and the presence of psychological factors has revealed some useful pointers to diagnosis in this syndrome. Some 70% probably suffered from polycystic ovarian disease. Hirsuties and post-pill amenorrhoea are strong pointers to such a diagnosis. Some 10% of the cases may have been psychogenic in origin and are notably found among non-hirsute patients with normal sized ovaries. Another 10% may have been physiological in nature. All other disorders accounted for no more than 10% of the cases. Anorexia nervosa and ovarian dysgenesis are particularly to be found among amenorrhoeic, non-hirsute patients with normal sized (or small) ovaries accounting for no less than 37% of this group in our series.
对467例月经过少和/或多毛患者的月经周期时长、体毛生长、卵巢大小及心理因素进行分析后,发现了该综合征诊断的一些有用线索。约70%的患者可能患有多囊卵巢疾病。多毛和停药后闭经是该诊断的有力线索。约10%的病例可能源于心理因素,尤其见于卵巢大小正常的非多毛患者。另外10%可能为生理性的。所有其他病症占病例总数不超过10%。神经性厌食和卵巢发育不全尤其见于闭经、非多毛且卵巢大小正常(或较小)的患者,在我们的系列研究中,这类患者占该组的比例不少于37%。