Galenok V A, Gostinskaia E V, Dikker V E, Korbman B I, Grek O P
Probl Endokrinol (Mosk). 1983 May-Jun;29(3):68-71.
The whole blood viscosity and the tissue oxygen balance were studied in rats and rabbits with alloxan diabetes. An augmentation of the blood viscosity was seen in female rats during diabetes latent period after injecting alloxan in a dose of 100 mg/kg. The blood viscosity is 3 times as high in diabetes, produced by the injection of alloxan in a dose of 200 mg/kg, and is characterized by severe hyperglycemia, simultaneously the tissue oxygen balance alteration is observed. Similarly the blood rheological properties and oxygen-transport functions are changed in female rabbits after injecting alloxan in a dose of 150 mg/kg. The blood viscosity of male rabbits with alloxan diabetes does not differ from that of the controls.
对用四氧嘧啶诱导糖尿病的大鼠和兔子的全血粘度及组织氧平衡进行了研究。给雌性大鼠注射100mg/kg剂量的四氧嘧啶后，在糖尿病潜伏期可见血液粘度增加。注射200mg/kg剂量四氧嘧啶所致糖尿病时，血液粘度升高3倍，伴有严重高血糖，同时观察到组织氧平衡改变。同样，给雌性兔子注射150mg/kg剂量四氧嘧啶后，血液流变学性质和氧运输功能发生改变。四氧嘧啶诱导糖尿病的雄性兔子的血液粘度与对照组无差异。
