Sundararaj T, Ilango B, Subramanian S
Trans R Soc Trop Med Hyg. 1983;77(2):194-7. doi: 10.1016/0035-9203(83)90067-6.
Counter immuno-electrophoresis (CIE) was used to detect the presence of Salmonella typhi antigen and antibodies in the sera of 123 suspected cases of enteric fever. Of these, 68 had been incompletely treated with various antibiotics before establishing the diagnosis. The sera of 31 (25%) of the 123 cases showed the presence of S. typhi antigen. Blood culture was positive for S. typhi in only one case. Antigen could be demonstrated in sera of patients with fever ranging from two to ten days. Antigen could also be demonstrated after ten days in sera of patients who had taken some antibiotics. There is no apparent relationship between the presence of antigen and antibodies in the sera, and no apparent relationship between the CIE antibody and Widal antibody titres.
采用对流免疫电泳（CIE）检测123例疑似伤寒患者血清中伤寒沙门菌抗原和抗体的存在情况。其中，68例在确诊前接受了各种抗生素的不完全治疗。123例患者中有31例（25%）的血清显示存在伤寒沙门菌抗原。仅1例血培养伤寒沙门菌呈阳性。发热2至10天患者的血清中可检测到抗原。服用过一些抗生素的患者在10天后的血清中也可检测到抗原。血清中抗原和抗体的存在之间没有明显关系，CIE抗体与肥达抗体滴度之间也没有明显关系。
