Levi M I
Zh Mikrobiol Epidemiol Immunobiol. 1983 Apr(4):98-103.
After mixing an antibody immunosorbent with Pasteurella pestis monovalent capsular antigen the concentration of the antigen in the free and bound states was evaluated. In this study the test points on the graph were found to be located on the lines characterizing different groups of antibodies differing in their affinity. The verification of the discrete structure of antibody affinity in 10 lots of hyperimmune horse serum showed the truth of this suggestion. The analysis of the role played by different groups of antibodies in binding the antigen indicated the prevailing role of a high-affinity group, especially in the zone with the excess of antibodies.
将抗体免疫吸附剂与鼠疫耶尔森菌单价荚膜抗原混合后，对游离态和结合态抗原的浓度进行了评估。在本研究中，发现图上的测试点位于表征亲和力不同的不同抗体组的曲线上。对10批超免疫马血清中抗体亲和力离散结构的验证表明了这一推测的正确性。对不同抗体组在结合抗原中所起作用的分析表明，高亲和力组起主要作用，尤其是在抗体过量的区域。
