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[醋酸盐和碳酸氢盐透析引起的头痛及脑电图改变]

[Headache and EEG changes caused by acetate and bicarbonate dialysis].

作者信息

Neyer U, Wöss E, Haller R, Kröss R

出版信息

Acta Med Austriaca. 1983;10(1):15-23.

PMID:6868943
Abstract

10 patients suffering from severe headache during Acetatedialysis were subsequently treated with Acetatedialysis (AD) and Bicarbonatedialysis (BD). During AD the headaches occurred more frequently and more intensely. After AD a deterioration of EEG-results was also seen more frequently than after BD. Urea, osmolarity and sodium in the blood as well as heart frequency and blood pressure showed no different variation. An essential difference was found in correction of the metabolic acidosis. After AD there could be seen a negative base excess and a fall in PaCO2, after BD the PaCO2 rose and the base excess was positive. Headaches and EEG-changes as signs of a cerebral dysfunction (disequilibrium syndrome) may perhaps be caused by a decrease of the cerebral blood flow. From our experience we recommend a change to BD for patients suffering from headaches during AD.

摘要

10名在醋酸盐透析期间患有严重头痛的患者随后接受了醋酸盐透析(AD)和碳酸氢盐透析(BD)治疗。在AD期间,头痛发作更频繁、更剧烈。与BD后相比,AD后脑电图结果恶化的情况也更常见。血液中的尿素、渗透压和钠以及心率和血压没有不同的变化。在代谢性酸中毒的纠正方面发现了一个本质差异。AD后可见碱剩余为负且PaCO2下降,BD后PaCO2升高且碱剩余为正。头痛和脑电图变化作为脑功能障碍(失衡综合征)的体征,可能是由脑血流量减少引起的。根据我们的经验,我们建议对在AD期间出现头痛的患者改用BD。

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