Hampl H, Klopp H W, Michels N, Mahiout A, Schilling H, Wolfgruber M, Schiller R, Hanefeld F, Kessel M
Proc Eur Dial Transplant Assoc. 1983;19:351-9.
Continuous long-time electroencephalographic (EEG) monitoring was performed during acetate and bicarbonate dialysis in 20 patients. Persisting normal basic activity of the EEG without neurological symptoms was found only during the course of bicarbonate dialysis. However, in acetate dialysis, during the decrease of arterial CO2 tension (PaCO2), we registered EEG disturbances with moderate to severe slowing, dysrhythmic activity and high voltage discharges. The decrease in PaCO2 and the deterioration in EEG activity in the patients during acetate dialysis was concomitant with severe neurological alterations, e.g. the typical symptoms of so-called 'disequilibrium' causing a cessation of dialysis in three patients.
对20例患者在进行醋酸盐和碳酸氢盐透析期间进行了长时间的脑电图（EEG）连续监测。仅在碳酸氢盐透析过程中发现脑电图基本活动持续正常且无神经症状。然而，在醋酸盐透析期间，随着动脉血二氧化碳分压（PaCO2）降低，我们记录到脑电图出现紊乱，表现为中度至重度减慢、节律紊乱活动和高电压放电。醋酸盐透析患者的PaCO2降低和脑电图活动恶化同时伴有严重的神经改变，例如所谓“失衡”的典型症状，导致3例患者透析终止。
