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用于药物剂量计算的理想体重的确定。

Determination of ideal body weight for drug dosage calculations.

作者信息

Robinson J D, Lupkiewicz S M, Palenik L, Lopez L M, Ariet M

出版信息

Am J Hosp Pharm. 1983 Jun;40(6):1016-9.

PMID:6869387
Abstract

Formulas for ideal body weight (IBW) in men and women were derived from the Metropolitan Life Insurance Company height and weight tables. Regression determinations of median weight versus height were performed for men and women. A program for a minicomputer was developed to generate plots for small, medium, and large frame sizes and for subjects of all frame sizes. Equations for ideal body weight were derived from the resulting data. For men of all frame sizes, IBW = 51.65 kg + 1.85 kg/inch of height greater than 5 feet. For women of all frame sizes, IBW = 48.67 kg + 1.65 kg/inch of height greater than 5 feet. More accurate estimates of IBW by frame size can be obtained using equations derived from the plots for men and women of each frame size. Estimates of IBW obtained by the widely used empirical method probably contain only minor errors. However, formulas derived from actual height and weight data should be used in pharmacokinetic determination of dosage regimens for some drugs.

摘要

男性和女性的理想体重(IBW)公式源自大都会人寿保险公司的身高体重表。对男性和女性的体重中位数与身高进行了回归测定。开发了一个小型计算机程序,以生成小、中、大三种体型以及所有体型受试者的图表。根据所得数据推导出理想体重方程。对于所有体型的男性,IBW = 51.65千克 + 超过5英尺部分每英寸身高1.85千克。对于所有体型的女性,IBW = 48.67千克 + 超过5英尺部分每英寸身高1.65千克。使用根据每种体型男性和女性图表得出的方程,可以更准确地按体型估算理想体重。通过广泛使用的经验方法获得的理想体重估计值可能仅包含微小误差。然而,在某些药物的给药方案药代动力学测定中,应使用根据实际身高和体重数据得出的公式。

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