Peck J J, Shields A B, Boyden A M, Dworkin L A, Nadal J W
Am J Surg. 1983 Jul;146(1):124-32. doi: 10.1016/0002-9610(83)90272-6.
Thirty patients with carcinoid tumors of the ileum over a recent 10-year period have been analyzed. Seventeen patients were symptomatic and 13 others were found to have tumors incidentally at autopsy or celiotomy. Patients with symptoms almost invariably had metastatic disease, yet preoperative diagnosis was rarely achieved. Arteriography in five patients with intestinal angina demonstrated encasement, kinking, and irregularity of mesenteric branches due to nodal metastasis. In five patients, each with liver metastasis, the classic carcinoid syndrome developed. Multiple primary carcinoid tumors were found in 9 of 30 patients (30 percent); 14 had an associated second malignant neoplasm (47 percent), most frequently colorectal carcinoma. En block surgical excision was the only effective therapy. Despite a prolonged natural history, the 5-year actuarial survival rate from the date of diagnosis was only 31 percent.
对最近10年间30例回肠类癌肿瘤患者进行了分析。17例有症状，另外13例在尸检或剖腹手术时偶然发现有肿瘤。有症状的患者几乎均有转移性疾病，但术前很少能做出诊断。5例有肠绞痛的患者行血管造影显示，由于淋巴结转移导致肠系膜分支被包绕、扭曲和不规则。5例均有肝转移的患者出现了典型的类癌综合征。30例患者中有9例（30%）发现有多发性原发性类癌肿瘤；14例有相关的第二种恶性肿瘤（47%），最常见的是结直肠癌。整块手术切除是唯一有效的治疗方法。尽管其自然病程较长，但从诊断之日起的5年精算生存率仅为31%。
