Ciordia H, Stuedemann J A, McCampbell H C
Am J Vet Res. 1983 Jun;44(6):1091-2.
Forty-five commercial-grade Angus calves naturally infected with tapeworms (Moniezia sp) were used in 2 controlled experiments to evaluate the cestocidal efficacy of 3 dosage levels of fenbendazole, methyl-5-(phenylthio) -2-benzimidazolecarbamate. In the 1st trial, 15 calves were divided into 3 groups of 5 each. One group served as nonmedicated controls. Other groups were drenched with fenbendazole at dosage rates of 10 and 15 mg/kg of body weight. Thirty calves used in the 2nd experiment were divided into 3 equal groups. One group served as nonmedicated controls and the other 2 groups were drenched at dosage rates of 7.5 and 10 mg/kg. Calves were necropsied 13 days after treatment. Doses of 10 and 15 mg/kg were 100% efficacious in reducing the number of tapeworm scolices, and a dose of 7.5 mg/kg was 91.7% effective. Signs of toxicosis were not observed in medicated cattle from time of treatment to necropsy.
45头自然感染绦虫（莫尼茨绦虫属）的商业级安格斯犊牛被用于2项对照实验，以评估3种剂量水平的芬苯达唑（甲基-5-（苯硫基）-2-苯并咪唑氨基甲酸酯）的杀绦虫效果。在第一项试验中，15头犊牛被分成3组，每组5头。一组作为未用药的对照组。其他组分别以10毫克/千克和15毫克/千克体重的剂量用芬苯达唑灌服。第二项实验中使用的30头犊牛被分成3组。一组作为未用药的对照组，其他2组分别以7.5毫克/千克和10毫克/千克的剂量灌服。在治疗后13天对犊牛进行剖检。10毫克/千克和15毫克/千克的剂量在减少绦虫头节数量方面100%有效，7.5毫克/千克的剂量有效率为91.7%。从治疗到剖检期间，在用药的牛中未观察到中毒迹象。
