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阿苯达唑对犊牛的杀绦虫活性。

Cestocidal activity of albendazole in calves.

作者信息

Ciordia H, McCampbell H C, Stuedemann J A

出版信息

Am J Vet Res. 1978 Mar;39(3):517-8.

PMID:637399
Abstract

Sixty commercial-grade calves naturally infected with tapeworms (Moniezia benedeni and M expansa) were used in a controlled experiment to evaluate the anthelmintic efficacy of 4 dose levels of albendazole. Calves were randomly divided into 5 groups of 12 each. One group served as non-medicated controls. Other groups were drenched with albendazole (methyl [5-(propyltion)-1H-benzimidazol-2-yl] carbamate) at dose rates of 20, 10, 5 and 2.5 mg/kg of body weight. Calves were necropsied 14 days after treatment. Doses of 20 and 10 mg/kg were 100% efficacious in reducing the number of tapeworm scolices, and doses of 5 and 2.5 mg/kg were 97.8%. Medicated cattle did not show signs of intoxication.

摘要

60头自然感染绦虫(贝氏莫尼茨绦虫和扩展莫尼茨绦虫)的商业级犊牛被用于一项对照实验,以评估4个剂量水平的阿苯达唑的驱虫效果。犊牛被随机分为5组,每组12头。一组作为未用药对照组。其他组分别以20、10、5和2.5毫克/千克体重的剂量率灌服阿苯达唑(甲基[5-(丙硫基)-1H-苯并咪唑-2-基]氨基甲酸酯)。治疗14天后对犊牛进行剖检。20毫克/千克和10毫克/千克的剂量在减少绦虫头节数量方面100%有效,5毫克/千克和2.5毫克/千克的剂量有效率为97.8%。用药的牛未表现出中毒迹象。

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2
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