Wüst J, Hardegger U
Antimicrob Agents Chemother. 1983 May;23(5):784-6. doi: 10.1128/AAC.23.5.784.
Resistance to clindamycin, erythromycin, and streptogramins in Clostridium difficile could be transferred to a susceptible strain by mixed culture at low frequencies (1 x 10(-8) to 4 - 10(-8) per donor cell). Transfer of tetracycline resistance occurred at frequencies of 3 x 10(-7) to 5 x 10(-7). No plasmid DNA involved in these transfers could be detected.
艰难梭菌对克林霉素、红霉素和链阳菌素的耐药性可通过低频率混合培养(每个供体细胞为1×10⁻⁸至4×10⁻⁸)转移至敏感菌株。四环素耐药性的转移频率为3×10⁻⁷至5×10⁻⁷。未检测到与这些转移相关的质粒DNA。