Green A A, MacFarlane J A
Arch Dis Child. 1983 Jul;58(7):535-7. doi: 10.1136/adc.58.7.535.
Two hundred and twenty seven children with a height below the 3rd or above the 97th centile were seen consecutively in the Oxford growth clinic. Their referral ages were analysed to determine the pattern of referral. Eighty seven per cent of the children had short stature. In 40% of these there was an organic reason for abnormal growth--the most common conditions being growth hormone deficiency, hypothyroidism, and Turner's syndrome--but the rest had genetic short stature or 'constitutional' delay in puberty. Many children who could have been treated effectively were referred too late, for effective treatment to ensure normal adult height because of this we have developed full sized percentile charts to screen populations of children so that abnormal stature can be recognised immediately.
227名身高低于第3百分位数或高于第97百分位数的儿童相继在牛津生长诊所就诊。分析了他们的转诊年龄以确定转诊模式。87%的儿童身材矮小。其中40%的儿童生长异常有器质性原因——最常见的情况是生长激素缺乏、甲状腺功能减退和特纳综合征——但其余儿童有遗传性身材矮小或青春期“体质性”延迟。许多本可得到有效治疗的儿童转诊过晚,无法确保获得正常成人身高的有效治疗。因此,我们绘制了全尺寸百分位图表来筛查儿童群体,以便能立即识别出异常身高情况。