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早期识别异常身高的方法。

Method for the earlier recognition of abnormal stature.

作者信息

Green A A, MacFarlane J A

出版信息

Arch Dis Child. 1983 Jul;58(7):535-7. doi: 10.1136/adc.58.7.535.

DOI:10.1136/adc.58.7.535
PMID:6870335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1628205/
Abstract

Two hundred and twenty seven children with a height below the 3rd or above the 97th centile were seen consecutively in the Oxford growth clinic. Their referral ages were analysed to determine the pattern of referral. Eighty seven per cent of the children had short stature. In 40% of these there was an organic reason for abnormal growth--the most common conditions being growth hormone deficiency, hypothyroidism, and Turner's syndrome--but the rest had genetic short stature or 'constitutional' delay in puberty. Many children who could have been treated effectively were referred too late, for effective treatment to ensure normal adult height because of this we have developed full sized percentile charts to screen populations of children so that abnormal stature can be recognised immediately.

摘要

227名身高低于第3百分位数或高于第97百分位数的儿童相继在牛津生长诊所就诊。分析了他们的转诊年龄以确定转诊模式。87%的儿童身材矮小。其中40%的儿童生长异常有器质性原因——最常见的情况是生长激素缺乏、甲状腺功能减退和特纳综合征——但其余儿童有遗传性身材矮小或青春期“体质性”延迟。许多本可得到有效治疗的儿童转诊过晚,无法确保获得正常成人身高的有效治疗。因此,我们绘制了全尺寸百分位图表来筛查儿童群体,以便能立即识别出异常身高情况。

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Genetic evaluation of short stature.身材矮小的基因评估。
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Low incidence of pathology detection and high cost of screening in the evaluation of asymptomatic short children.

本文引用的文献

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Clin Endocrinol (Oxf). 1979 Jul;11(1):15-38. doi: 10.1111/j.1365-2265.1979.tb03043.x.
在评估无症状身材矮小儿童时,病理检测发生率低,筛查费用高。
J Pediatr. 2013 Oct;163(4):1045-51. doi: 10.1016/j.jpeds.2013.04.002. Epub 2013 May 21.
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The diagnostic work up of growth failure in secondary health care; an evaluation of consensus guidelines.二级医疗保健中生长发育迟缓的诊断检查;共识指南评估
BMC Pediatr. 2008 May 13;8:21. doi: 10.1186/1471-2431-8-21.
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Equipping the community to measure children's height: the reliability of portable instruments.使社区具备测量儿童身高的能力:便携式仪器的可靠性
Arch Dis Child. 1994 Jun;70(6):469-71. doi: 10.1136/adc.70.6.469.
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Evaluation of a district growth screening programme: the Oxford Growth Study.一项地区生长发育筛查项目的评估:牛津生长发育研究
Arch Dis Child. 1993 Sep;69(3):361-5. doi: 10.1136/adc.69.3.361.
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Short stature.身材矮小。
Br Med J (Clin Res Ed). 1984 Nov 17;289(6455):1371-3. doi: 10.1136/bmj.289.6455.1371.
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When are we diagnosing growth hormone deficiency?我们何时诊断生长激素缺乏症?
Arch Dis Child. 1986 Feb;61(2):110-2. doi: 10.1136/adc.61.2.110.
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Management of patients with congenital hypothyroidism.先天性甲状腺功能减退症患者的管理。
Br Med J (Clin Res Ed). 1985 May 18;290(6480):1485-9. doi: 10.1136/bmj.290.6480.1485.