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内淋巴囊的细胞内和细胞外离子含量。

Intracellular and extracellular ion content of the endolymphatic sac.

作者信息

Amano H, Orsulakova A, Morgenstern C

出版信息

Arch Otorhinolaryngol. 1983 Apr;237(3):273-7. doi: 10.1007/BF00453732.

DOI:10.1007/BF00453732
PMID:6870660
Abstract

The Cl- activity in the endolymph of the endolymphatic sac and in the cochlear duct was measured with Cl- sensitive double-barreled microelectrodes. The Cl- activity in the endolymphatic sac fluid was lower than in the cochlear duct. A small, positive, DC potential was recorded in the endolymphatic sac. During anoxia, the DC potential decreased while the Cl- activity in the endolymphatic sac increased. The K/Na ratio in the epithelial cells and subepithelial tissue of endolymphatic sac was measured using the LAMMA technique. The K/Na ratio in the epithelial cells decreased after ethacrynic acid injection (60 mg/kg i.v.). These findings suggest that chloride in the endolymphatic sac is actively transported inward and outward.

摘要

使用氯离子敏感双管微电极测量内淋巴囊内淋巴和蜗管内淋巴中的氯离子活性。内淋巴囊液中的氯离子活性低于蜗管中的氯离子活性。在内淋巴囊中记录到一个小的正直流电位。缺氧时,直流电位降低,而内淋巴囊中氯离子活性增加。使用激光微探针质谱分析法(LAMMA技术)测量内淋巴囊上皮细胞和上皮下组织中的钾/钠比。注射依他尼酸(60毫克/千克静脉注射)后,上皮细胞中的钾/钠比降低。这些发现表明,内淋巴囊中的氯离子被主动地向内和向外转运。

相似文献

1
Intracellular and extracellular ion content of the endolymphatic sac.内淋巴囊的细胞内和细胞外离子含量。
Arch Otorhinolaryngol. 1983 Apr;237(3):273-7. doi: 10.1007/BF00453732.
2
Recent advances in laser microprobe mass analysis (LAMMA) of inner ear tissue.
Scan Electron Microsc. 1985(Pt 1):393-405.
3
Functional and morphological findings of endolymphatic sac.内淋巴囊的功能和形态学研究结果
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Endolymphatic sac obstruction. Biochemical studies.内淋巴囊梗阻。生化研究。
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Ionic activities of the inner ear fluid and ionic permeabilities of the cochlear duct in endolymphatic hydrops of the guinea pig.
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Ion transport in the endolymphatic space.内淋巴间隙中的离子转运。
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引用本文的文献

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Ion transport its regulation in the endolymphatic sac: suggestions for clinical aspects of Meniere's disease.内淋巴囊中的离子转运及其调节:对梅尼埃病临床方面的启示
Eur Arch Otorhinolaryngol. 2017 Apr;274(4):1813-1820. doi: 10.1007/s00405-016-4362-1. Epub 2016 Nov 1.
2
Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression.内淋巴囊液体吸收失败会导致耳蜗扩大,从而导致缺乏 pendrin 表达的小鼠耳聋。
PLoS One. 2010 Nov 17;5(11):e14041. doi: 10.1371/journal.pone.0014041.
3
The detailed localization pattern of Na+/K+/2Cl- cotransporter type 2 and its related ion transport system in the rat endolymphatic sac.

本文引用的文献

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Distribution, structure, and function of dark cells in the vestibular labyrinth.前庭迷路中暗细胞的分布、结构和功能。
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Cation transport in the ampulla of the semicircular canal and in the endolymphatic sac.
Arch Otorhinolaryngol. 1987;244(1):61-5. doi: 10.1007/BF00453493.
5
The difference in endocochlear and endolymphatic sac d.c. potentials in response to furosemide and canrenoate as diuretics.
Eur Arch Otorhinolaryngol. 1990;247(6):371-3. doi: 10.1007/BF00179010.
4
Potassium level in endolymphatic sac of guinea pigs in vivo.豚鼠体内内淋巴囊中的钾离子水平。
Arch Otorhinolaryngol. 1979;222(1):77-8. doi: 10.1007/BF00456341.