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内淋巴囊形态与功能的相关方面。

Aspects on endolymphatic sac morphology and function.

作者信息

Lundquist P G

出版信息

Arch Otorhinolaryngol. 1976 Sep 16;212(4):231-40. doi: 10.1007/BF00453671.

DOI:10.1007/BF00453671
PMID:990076
Abstract

Morphological evidence indicate that the main function of the endolymphatic sac is to act as a reabsorptive and defensive mechanism for the inner ear. This activity is markedly enhanced in labyrinthine trauma, such as injection of foreign particles into the labyrinth, blocking of the endolymphatic duct, and cryosurgical destruction of vestibular sensory epithelia. Light and dark epithelial cells of the intermediate portion of the sac are capable of reabsorbing endolymph and digesting cellular debris respectively. The extensive capillary network surrounding the endolymphatic sac exhibits endothelial characteristics suggestive of active fluid transport. The "dynamic-flow theory" of endolymph circulation suggests that a radial-flow should be considered for energy metabolism and ion exchange around the sensory cell regions whereas a longitudinal-flow should be considered for reabsorption of endolymph and disposal of high molecular waist products and debris by the endolymphatic sac. The earlier concepts of endolymph circulation thus need not any longer be considered conflicting.

摘要

形态学证据表明,内淋巴囊的主要功能是作为内耳的重吸收和防御机制。在迷路创伤中,如向迷路注射异物、阻塞内淋巴管以及对前庭感觉上皮进行冷冻手术破坏时,这种活动会显著增强。囊中间部分的明细胞和暗细胞分别能够重吸收内淋巴和消化细胞碎片。围绕内淋巴囊的广泛毛细血管网络表现出提示活跃液体运输的内皮特征。内淋巴循环的“动态流动理论”表明,在感觉细胞区域周围进行能量代谢和离子交换时应考虑径向流动,而在内淋巴的重吸收以及内淋巴囊对高分子量废物和碎片的处理时应考虑纵向流动。因此,早期的内淋巴循环概念不再需要被认为是相互矛盾的。

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Aspects on endolymphatic sac morphology and function.内淋巴囊形态与功能的相关方面。
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本文引用的文献

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The diaphragm of capillary endothelial fenestrations.毛细血管内皮窗孔的隔膜
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Circulation of the inner ear fluids.内耳液体的循环。
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非综合征性大前庭导水管的遗传决定因素:综述
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