Parker D E, Tjernström O, Ivarsson A, Gulledge W L, Poston R L
Aviat Space Environ Med. 1983 May;54(5):402-9.
This paper addresses the "fluid shift theory" of space motion sickness. The primary purpose of our research was the development of procedures to assess individual differences in response to rostral body fluid shifts on earth. Experiment I examined inner ear fluid pressure changes during head-down tilt in intact human beings. Tilt produced reliable changes. Differences among subjects and between ears within the same subject were observed. Experiment II examined auditory threshold changes during tilt. Tilt elicited increased auditory thresholds, suggesting that sensory depression may result from increased inner ear fluid pressure. Additional observations on rotation magnitude estimation during head-down tilt, which indicate that rostral fluid shifts may depress semicircular canal activity, are briefly described. The results of this research suggest that the inner ear pressure and auditory threshold shift procedures could be used to assess individual differences among astronauts prior to space flight. Results from the terrestrial observations could be related to reported incidence/severity of motion sickness in space and used to evaluate the fluid shift theory of space motion sickness.
本文探讨了太空晕动病的“体液转移理论”。我们研究的主要目的是开发一些程序，以评估个体在地球上对头部体液向前转移的反应差异。实验一检测了完整人体在头向下倾斜时内耳的流体压力变化。倾斜产生了可靠的变化。观察到了不同受试者之间以及同一受试者两耳之间的差异。实验二检测了倾斜过程中的听觉阈值变化。倾斜引发了听觉阈值升高，这表明感觉功能下降可能是内耳流体压力增加所致。本文还简要描述了关于头向下倾斜时旋转幅度估计的其他观察结果，这些结果表明头部体液向前转移可能会抑制半规管活动。这项研究的结果表明，内耳压力和听觉阈值变化程序可用于在太空飞行前评估宇航员之间的个体差异。地面观察结果可与太空中晕动病的报告发病率/严重程度相关联，并用于评估太空晕动病的体液转移理论。
