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蛋白脂质与牛主动脉钙化,体外研究

Proteolipid and bovine aorta calcification, in vitro.

作者信息

Ennever J, Riggan L J

出版信息

Atherosclerosis. 1983 Apr;47(1):27-34. doi: 10.1016/0021-9150(83)90068-0.

Abstract

Proteolipid was examined for nucleation of bovine aorta calcification. Tissue homogenates were tested for in vitro calcifiability before and after lipid extraction followed by similar tests of the extract and its fractions. The tissue calcified before but not after lipid extraction. Of the lipid fractions, only proteolipid calcified. Within the constraints imposed, proteolipid is required for initiation of bovine aorta calcification, in vitro.

摘要

对蛋白脂质进行了牛主动脉钙化成核作用的检测。在脂质提取前后对组织匀浆进行体外钙化能力测试,随后对提取物及其组分进行类似测试。脂质提取前组织发生钙化,提取后则未发生钙化。在脂质组分中,只有蛋白脂质发生钙化。在规定的条件下,体外牛主动脉钙化的起始需要蛋白脂质。

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