Sconzo G, Roccheri M C, Di Carlo M, Di Bernardo M G, Giudice G
Cell Differ. 1983 Jun;12(6):317-20. doi: 10.1016/0045-6039(83)90010-6.
Embryos dissociated into cells retain the stage-specific response to heat shock. The dissociated cells, irrespectively of whether they are reaggregated or not, undergo the developmental changes in their ability to respond to heat shock, at the same time as the entire embryos. The conclusion of the present experiments is that sea urchin embryonic cells become responsive to heat shock and produce heat shock proteins even in the absence of cell interactions.
解离成细胞的胚胎保留了对热休克的阶段特异性反应。解离后的细胞,无论是否重新聚集,都会在与整个胚胎相同的时间内,经历其对热休克反应能力的发育变化。本实验的结论是,即使在没有细胞相互作用的情况下,海胆胚胎细胞也会对热休克产生反应并产生热休克蛋白。