Roccheri M C, Sconzo G, Di Carlo M, Di Bernardo M G, Pirrone A, Gambino R, Giudice G
Differentiation. 1982;22(3):175-8. doi: 10.1111/j.1432-0436.1982.tb01246.x.
The production of heat-shock proteins in sea urchin embryos is accompanied by the appearance at the polysomal level of their relative mRNAs, as shown by their translation in a cell-free system; thus suggesting that the regulation of their production occurs at a transcriptional level. The mechanism for the inhibition of the bulk protein synthesis and for its reversal on the other hand should be looked for at a posttranscriptional level, since both these phenomena occur also in the presence of actinomycin D. The heat-shock proteins produced as early as at the mesenchyme blastula stage persist within the embryo at least till the pluteus stage.
海胆胚胎中热休克蛋白的产生伴随着其相关mRNA在多核糖体水平的出现，这通过它们在无细胞系统中的翻译得以证明；因此表明它们产生的调节发生在转录水平。另一方面，大量蛋白质合成的抑制及其逆转机制应该在转录后水平寻找，因为这两种现象在放线菌素D存在的情况下也会发生。早在间充质囊胚阶段产生的热休克蛋白至少在胚胎内持续到长腕幼虫阶段。
