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[用去氧孕烯和利苏瑞ide阻断苯甲酸雌二醇所致腺垂体增生 - 组织学研究结果]

[Blockade of estradiol benzoate hyperplasia of the adenohypophysis with Deprenon and lisuride - histological findings].

作者信息

Dusková J, Schreiber V, Pribyl T, Jahodová J

出版信息

Cesk Patol. 1983 May;19(2):101-7.

PMID:6872045
Abstract

Three-week administering of Estradiolbenzoate to male rats results in hyperplasia of adenohypophysis with increase of Orange G slightly positive cells and chromophobe cells, loosening of structure giving a trabecular picture, and stressed vascularization. Simultaneous administering of Ergoline compounds (Deprenon, Lisuride) rather limited the transformation. However, the differentiation of single pituitary cells due to Estradiolbenzoate remained substantially uninfluenced.

摘要

对雄性大鼠连续三周给予苯甲酸雌二醇会导致腺垂体增生,橙色G轻度阳性细胞和嫌色细胞增多,结构疏松呈小梁状,血管形成增强。同时给予麦角林化合物(去甲雄三烯醇酮、利苏力特)会相当程度地限制这种转变。然而,苯甲酸雌二醇引起的单个垂体细胞分化基本未受影响。

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