Fischer F, Gärtner J
Exp Eye Res. 1983 Jul;37(1):55-64. doi: 10.1016/0014-4835(83)90149-5.
Twelve months after onset of streptozotocin-induced diabetes in rats, the basal lamina width of peripheral retinal capillaries, as measured with two different morphometric methods, is increased only in the basal lamina regions adjacent to perivascular glial cells. In the region between endothelial cells and pericytes no increase of thickness was observed. These facts support the suggestion of a predominantly glial (neuroectodermal) contribution to basal lamina thickening of retinal capillaries in diabetes mellitus. No correlation exists between the degree of basal lamina thickening at the different anatomic sites. Furthermore, no clear-cut correlation was found between basal lamina thickening and severity of the metabolic disease.
在大鼠链脲佐菌素诱导的糖尿病发病十二个月后，用两种不同的形态测量方法测量，周边视网膜毛细血管的基底膜宽度仅在与血管周围神经胶质细胞相邻的基底膜区域增加。在内皮细胞和周细胞之间的区域未观察到厚度增加。这些事实支持了在糖尿病中神经胶质（神经外胚层）对视网膜毛细血管基底膜增厚起主要作用的观点。不同解剖部位的基底膜增厚程度之间没有相关性。此外，在基底膜增厚与代谢疾病严重程度之间未发现明确的相关性。
