Rogalski C J, Lahmeyer H W
Int J Addict. 1983 Apr;18(3):407-18. doi: 10.3109/10826088309039357.
Fourteen male heroin addicts being detoxified on methadone and 14 male pentazocine addicts being detoxified drug-free were observed over a 24-hour period for 2 weeks in their sleeping patterns to assess the effects of flurazepam upon sleep during withdrawal. Results of objective and subjective measures find that flurazepam use is associated with more objective nighttime arousals and less total sleep for the heroin group compared to the pentazocine group. Heroin patients felt they had a poorer quality of sleep and took flurazepam more frequently than did the pentazocine patients. Heroin patients' assessments of their sleep and number of arousals correlated poorly with observations.
对14名正在用美沙酮进行戒毒的男性海洛因成瘾者和14名正在进行无药戒毒的男性喷他佐辛成瘾者，在两周内的24小时时间段内观察他们的睡眠模式，以评估氟西泮在戒毒期间对睡眠的影响。客观和主观测量结果发现，与喷他佐辛组相比，海洛因组使用氟西泮与更多的夜间客观觉醒及更少的总睡眠时间相关。海洛因成瘾患者感觉他们的睡眠质量较差，且比喷他佐辛成瘾患者更频繁地服用氟西泮。海洛因成瘾患者对自己睡眠及觉醒次数的评估与观察结果相关性较差。
