Maclean A B, Doig J R, Aickin D R
Br J Obstet Gynaecol. 1978 Aug;85(8):597-601. doi: 10.1111/j.1471-0528.1978.tb14927.x.
Six patients with severe pre-eclampsia were found to have low central venous pressures. This was considered to be an indication that hypovolaemia was present, depsite concurrent generalized oedema. Treatment with sufficient intravenous saline and albumin, to restore the central venous pressure to normal, resulted in improved renal function and avoidance of permanent renal impairment in all cases. These observations support the view that diuretics should not be administered to patients with pre-eclampsia.
六名重度子痫前期患者被发现中心静脉压较低。尽管同时存在全身性水肿，但这被认为是存在血容量不足的迹象。通过静脉输注足够的生理盐水和白蛋白进行治疗，使中心静脉压恢复正常，所有病例的肾功能均得到改善，且避免了永久性肾功能损害。这些观察结果支持了不应给子痫前期患者使用利尿剂的观点。
