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麻醉犬在心房扩张前、扩张期间及扩张后的血浆血管加压素浓度。

Plasma vasopressin concentration in the anaesthetized dog before, during and after atrial distension.

作者信息

Ledsome J R, Ngsee J, Wilson N

出版信息

J Physiol. 1983 May;338:413-21. doi: 10.1113/jphysiol.1983.sp014680.

Abstract

Plasma vasopressin (AVP) concentration in dogs anaesthetized with chloralose was measured by radioimmunoassay and was within the range of 2-5 pg/ml. during control periods. Distension of the left atrium led within 2 min to a fall in plasma AVP concentration which reached a steady lower value within 4 min. After cessation of atrial distension the AVP concentration returned to pre-distention values within 4 min. Cooling the cervical vagosympathetic nerves to 8-10 degrees C led to a rise in plasma AVP concentration. Atrial distension during cooling of the vagi resulted in a further increase of plasma AVP concentration.

摘要

用放射免疫分析法测定了用氯醛糖麻醉的狗的血浆血管加压素(AVP)浓度,在对照期内其浓度范围为2 - 5 pg/ml。左心房扩张在2分钟内导致血浆AVP浓度下降,并在4分钟内达到稳定的较低值。心房扩张停止后,AVP浓度在4分钟内恢复到扩张前的值。将颈迷走交感神经冷却至8 - 10摄氏度会导致血浆AVP浓度升高。迷走神经冷却期间的心房扩张会导致血浆AVP浓度进一步升高。

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