Young J D, Tucker E M, Ellory J C
Biochim Biophys Acta. 1978 Aug 17;511(3):513-6. doi: 10.1016/0005-2736(78)90286-9.
An amino acid transport defect which occurs in the erythrocytes of adult sheep is also present in foetal erythrocytes from newborn lambs which have inherited the lesion. The transport defect in erythrocytes from adult sheep is associated with high intracellular levels of ornithine and lysine and a markedly diminished GSH concentration. Although the lesion in foetal cells also results in the accumulation of ornithine and lysine, the intracellular GSH concentration is only moderately diminished.
成年绵羊红细胞中出现的一种氨基酸转运缺陷，在继承了该病变的新生羔羊的胎儿红细胞中也存在。成年绵羊红细胞中的转运缺陷与细胞内高水平的鸟氨酸和赖氨酸以及明显降低的谷胱甘肽浓度有关。虽然胎儿细胞中的病变也会导致鸟氨酸和赖氨酸的积累，但细胞内谷胱甘肽浓度仅适度降低。
