Nozaki M, Mitsuhashi N, Maehara Y, Nakano T, Niibe H
Gan No Rinsho. 1983 Feb;29(2):A-9, 143-46.
The patient was a 21-year-old man with SVC syndrome due to a large anterior mediastinal mass. Following radiotherapy which improved his condition, thoracotomy was performed, however, total resection failed. Despite postoperative re-irradiation, his condition worsened rapidly and he died five months after the onset of his symptoms. The neoplasm was composed of a yolk sac tumor producing alpha-fetoprotein. Yolk sac tumors of the mediastinum are rare and lethal. Recent reports indicate that cis-platinum may be highly effective in germ cell tumors. Therefore, radiotherapy combined with cis-platinum may be improved the survival of patients with yolk sac tumor.
该患者为一名21岁男性，因前纵隔巨大肿块导致上腔静脉综合征。放疗后病情有所改善，随后进行了开胸手术，但未能完全切除肿瘤。尽管术后再次放疗，其病情仍迅速恶化，症状出现五个月后死亡。肿瘤由产生甲胎蛋白的卵黄囊瘤组成。纵隔卵黄囊瘤罕见且致命。最近的报告表明，顺铂可能对生殖细胞肿瘤高度有效。因此，放疗联合顺铂可能提高卵黄囊瘤患者的生存率。
