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[鞍上松果体生殖细胞瘤神经外转移尸检病例]

[Autopsy case of extra-neural metastasis of suprasellar pineal germinoma].

作者信息

Shinmura F, Takayasu K, Sakata R, Ariwa R, Takagi S

出版信息

Gan No Rinsho. 1983 Jun;29(7):832-7.

PMID:6876451
Abstract

A 19-year-old boy was admitted with a suprasellar tumor. On May, 1980 he underwent craniotomy and subtotal tumor removal. The pathological diagnosis was germinoma. In July, 1981, a solitary angiomatous tumor appeared in the left back skin and was resected. The pathological diagnosis was choriocarcinoma, thus, a final diagnosis of suprasellar choriocarcinoma was made. At the first admission, his LH was 100 miu/ml; FSH, 2.4 miu/ml, while; at the second admission, LH was 500 miu/ml; FSH, 9.9 miu/ml, HCG, 13000 miu/ml. Irradiation combined with chemotherapy brought no improvement of his symptoms and he died. At autopsy, multiple metastatic foci were recognized in the lungs, liver, kidney, intestine, skin and brain.

摘要

一名19岁男孩因鞍上肿瘤入院。1980年5月,他接受了开颅手术及肿瘤次全切除。病理诊断为生殖细胞瘤。1981年7月,左侧背部皮肤出现一个孤立的血管瘤样肿瘤并被切除。病理诊断为绒毛膜癌,因此最终诊断为鞍上绒毛膜癌。首次入院时,他的促黄体生成素(LH)为100毫国际单位/毫升;促卵泡生成素(FSH)为2.4毫国际单位/毫升,而第二次入院时,LH为500毫国际单位/毫升;FSH为9.9毫国际单位/毫升,人绒毛膜促性腺激素(HCG)为13000毫国际单位/毫升。放疗联合化疗未能改善他的症状,他最终死亡。尸检时,在肺、肝、肾、肠、皮肤和脑内发现了多个转移灶。

相似文献

1
[Autopsy case of extra-neural metastasis of suprasellar pineal germinoma].[鞍上松果体生殖细胞瘤神经外转移尸检病例]
Gan No Rinsho. 1983 Jun;29(7):832-7.
2
[A case of intracranial germinoma with multiple remote metastases (author's transl)].1例颅内生殖细胞瘤伴多发远处转移(作者译)
No Shinkei Geka. 1980 Jun;8(6):563-70.
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[A case of pineal pure germinoma metastasized to the lumbosacral extradural space 8 years after initial therapy. Case report and review of literature].[1例松果体纯生殖细胞瘤在初始治疗8年后转移至腰骶部硬膜外间隙。病例报告及文献复习]
No Shinkei Geka. 2006 Jul;34(7):745-52.
4
Pineal germinoma with syncytiotrophoblastic giant cells: a case with panhypopituitarism and isosexual pseudopuberty.伴有合体滋养层巨细胞的松果体生殖细胞瘤:一例全垂体功能减退和同性假性性早熟病例
Hum Pathol. 1984 Mar;15(3):285-7. doi: 10.1016/s0046-8177(84)80192-6.
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Cytologic diagnosis of pineal germinoma in cerebrospinal fluid and sputum.脑脊液和痰液中松果体生殖细胞瘤的细胞学诊断
Acta Cytol. 1979 Jul-Aug;23(4):341-6.
6
[Problems on recurrence after removal of teratoma in pineal region--an experience of recurrence of pineal teratoma 4 years after tumor removal].松果体区畸胎瘤切除术后复发问题——1例松果体畸胎瘤切除术后4年复发的经验
No To Shinkei. 1982 Nov;34(11):1107-15.
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[Extraneural metastasis of pineal germinoma through a ventriculoperitoneal shunt, following histological change].[松果体生殖细胞瘤经脑室腹腔分流术后组织学改变出现神经外转移]
No Shinkei Geka. 1999 Mar;27(3):269-74.
8
[A case report of germinoma with syncytiotrophoblastic giant cells (STGC) in the basal ganglia].
No Shinkei Geka. 1996 Mar;24(3):267-71.
9
[Primary intracranial germ cell tumor in the right basal ganglia and its vicinity area--a report of the case with germinoma and choriocarcinoma histologically].[右侧基底节及其附近区域原发性颅内生殖细胞肿瘤——1例组织学为生殖细胞瘤和绒毛膜癌的病例报告]
No Shinkei Geka. 1983 Jan;11(1):73-80.
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[Glioblastoma multiforme with liver metastasis--case report].[多形性胶质母细胞瘤伴肝转移——病例报告]
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引用本文的文献

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Treatment outcomes and risk factors of patients with intracranial germ cell tumour with choriocarcinoma element or β-HCG level higher than 500 IU/L.颅内生殖细胞肿瘤伴绒癌成分或β-HCG 水平高于 500IU/L 患者的治疗结果和相关风险因素。
J Neurooncol. 2024 Jan;166(2):331-339. doi: 10.1007/s11060-024-04565-x. Epub 2024 Jan 18.
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Liver metastasis in an adolescent treated for third ventricle germ cell tumor.一名接受第三脑室生殖细胞瘤治疗的青少年发生肝转移。
Indian J Med Paediatr Oncol. 2014 Apr;35(2):181-3. doi: 10.4103/0971-5851.138999.
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Prognostic factors and therapeutic problems of primary intracranial choriocarcinoma/germ-cell tumors with high levels of HCG.
伴有高水平人绒毛膜促性腺激素的原发性颅内绒毛膜癌/生殖细胞肿瘤的预后因素及治疗问题
J Neurooncol. 2004 Jan;66(1-2):225-40. doi: 10.1023/b:neon.0000013499.74404.81.